Which sex-linked disorder is caused by a chromosome abnormality and is typically identified by puberty, with incomplete maturation of male sexual characteristics?

Which sex-linked disorder is caused by a chromosome abnormality and is typically identified by puberty, with incomplete maturation of male sexual characteristics?

• A. Klinefelter's Syndrome
• B. Down Syndrome
• C. Spina Bifida
• D. Talipes

Answer: (A)

When a male has an extra X chromosome, the result is a chromosome abnormality that affects how puberty unfolds. In Klinefelter’s syndrome, the male has an extra X chromosome (XXY). This disrupts normal testicular development and lowers testosterone levels, so secondary male sexual characteristics don’t mature fully during puberty. That leads to delayed or incomplete development of features like facial and body hair, deeper voice, muscle mass, and often fertility issues. It’s a chromosomal condition arising from an error in cell division, rather than a single-gene inheritance, and it’s typically noticed when puberty doesn’t proceed as expected. The other disorders listed aren’t caused by an extra sex chromosome and don’t present with puberty-related incomplete maturation of male traits.

When a male has an extra X chromosome, the result is a chromosome abnormality that affects how puberty unfolds. In Klinefelter’s syndrome, the male has an extra X chromosome (XXY). This disrupts normal testicular development and lowers testosterone levels, so secondary male sexual characteristics don’t mature fully during puberty. That leads to delayed or incomplete development of features like facial and body hair, deeper voice, muscle mass, and often fertility issues. It’s a chromosomal condition arising from an error in cell division, rather than a single-gene inheritance, and it’s typically noticed when puberty doesn’t proceed as expected. The other disorders listed aren’t caused by an extra sex chromosome and don’t present with puberty-related incomplete maturation of male traits.